Endocrine Abstracts

Introduction: The number of elderly with cognitive decline has been increasing. Several studies have shown that diabetes is a risk factor for cognitive impairment. Chronic hyperglycemia is implicated, probably by promoting the development of cerebral microvascular disease but physiopathology is complicated.Methods: The study involved thirty-seven diabetic patients hospitalized in the department C of National Institute of Nutrition and Food Technology of ...

Introduction: Low high-density lipoprotein (HDL) is a frequent metabolic abnormality, associated with diabetes, may increase the cardiovascular risk of patients with type 2 diabetes. We aimed in this study, determine the prevelence of hypo HDL cholesterol and assess the associated cardiovascular risk.Method: It is a retrospective study, including 184 type 2 diabetic patients, conducted in the department C of the National Institute of Nutrition of Tunis d...

Introduction: Sudden idiopathic deafness is often a diagnosis of elimination. It is defined by an isolated sensorineural hearing loss (sensorineural deafness) unilateral and without obvious etiology but a vascular hypothesis is plausible. We report in this context a case of unilateral sudden hearing loss revealing type 2 diabetes (T2DM).Observation: This is a 40-year-old man, sedentary, with no particular pathological history, a 20-pack/year smoker and o...

Diabetes is a common disease with concomitant oral manifestations that impact dental care.Purpose: To investigate oral health awareness, oral hygiene and behavior in adults with diabetes.Subjects and methods: This study involved interviews with a sample of 30 patients with diabetes type 2 followed in the C department of the National Institute of Nutrition in Tunis using a questionnaire study on oral health behavior and awareness.</...

Excessive daytime sleepiness (EDS) is commonly considered a cardinal sign of sleep apnea; however, the mechanism underlying the association is unclear.Purpose: The purpose of this study is to investigate the daytime sleepiness in patients with diabetes.Methods: Participants were 30 adults with type 2 diabetes (T2DM) followed in the C department of the National Institute of Nutrition in Tunis. Subjective sleepiness was assessed usin...

Background and Aim: Patients with diabetes mellitus(DM) are at increased risk of infections, with the urinary tract being the most frequent infection site. High rates of antibiotic prescription, including broad-spectrum antibiotics, for urinary tract infection (UTI) in these patients may further induce the development of antibiotic-resistant urinary pathogens. The aim of our study is to determine the epidemiology of UTI and resistance patterns of bacterial isolates in patients...

Introduction: Persons with diabetes may need to be hospitalized in order to improve diabetes balance. We aimed to evaluate the benefits from hospitalization in a diabetes department on glycemic parameters.Method: It was a descriptive cross-sectional study conducted on diabetic patients consulting for the first time after a hospitalization in the department (C) of the National Institute of Nutrition of Tunis for the management of a poorly controlled diabe...

Introduction: The glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme deficiency in humans. In red blood cells, the pentose phosphate pathway is the only source of nicotinamide adenine dinucleotide (NADPH), and defense mechanisms against oxidative damage are highly dependent on G6PD activity. The occurrence of acute haemolysis in patient with G6PD deficiency and diabetes has been reported and ascribed to various mechanisms. Her we report a case of pat...

The pregnancies conceived after chemotherapy for trophoblastic neoplasia should be followed with clinical surveillance due to higher rates of some pregnancy complications especially when associated with diabetes mellitus. We report the case of a 30-year-old nulliparous woman, obese, had been diagnosed with type 2 diabetes mellitus for 10 years, without micro or macrovascular complications, treated by conventional insulin therapy, with a history of low-risk gestational chorioca...

IntroductionInsulin therapy can lead to obesity which can affect the comorbidities of the type 2 diabetes. Should we consider the body mass index (BMI) before prescribing it?MethodsOur study is prospective, randomized and comparative.We recruited patients with type 2 diabetes hospitalized for a switching to insulin in the C department of diabetology and nutrition at the National Nutrition Institute in Tunis, ...